Nuclear-cytoplasmic interactions during ovine oocyte maturation

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Nuclear-cytoplasmic interactions during ovine oocyte maturation.

The present studies have been undertaken to investigate the interactions that occur between the nucleus and cytoplasm of ovine oocytes at various stages during meiotic maturation. We report that the nucleus of ovine fully grown dictyate stage oocytes can be efficiently removed by a microsurgical enucleation procedure. It is demonstrated that between the initiation of maturation and germinal ves...

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P-64: The Effect of Ovine Oocyte Diameter on Nuclear Maturation

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Leptin enhances oocyte nuclear and cytoplasmic maturation via the mitogen-activated protein kinase pathway.

Recent studies have suggested that leptin has a central role in female reproduction, including ovarian function. The leptin receptor (Ob-R) has six isoforms and can signal through either the MAPK or the Janus-activated kinase/signal transducer and activator of transcription signal-transduction pathway, depending on the isoform. Expression of Ob-R has been reported in human and mouse oocytes; ho...

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Nuclear and cytoplasmic determinants involved in the regulation of mammalian oocyte maturation.

The requisite endpoint of mammalian oocyte maturation, whether in vivo or in vitro, is a metaphase II oocyte which is able to be fertilized and which can eventually support normal embryonic development. Oocytes which have been matured in vivo basically fulfill these criteria. On the other hand, a completely different situation exists when these cells are isolated from the ovaries and cultured i...

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ژورنال

عنوان ژورنال: Development

سال: 1991

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.111.1.171